Issei Sagawa in 1981 murdered and cannibalized Renee Hartevelt who was attending school in Paris France. 
7 3/4" x 10" drawing / portrait. On the bottom he has written, "Gokumi, beautiful actress married with French famous guy. Drawn by Issei Sagawa."  Hand signed again on the bottom left, Issei Sagawa.

Issei Sagawa Gokumi Portrait Signed Twice